HSLS Systematic Review Program

Want additional guidance?

• Read this article from JBI: Best practice guidance and reporting items for the development of scoping review protocols

PRISMA for Systematic Review Protocols was published in 2015 to provide guidance on the development and reporting of protocols for systematic reviews

• PRISMA P 2015 Statement Paper

• PRISMA P Explanation & Elaboration Paper

• Organizations such as the Cochrane Collaboration, Joanna Briggs Institute, or Campbell Collaboration have their own guidance and templates for systematic reviews - please contact the organizations for additional information

Examples of published protocols can be viewed in the BioMed Central journal Systematic Reviews (on the home page, enter "protocol" in the search box)

• The rigor and trustworthiness of a systematic review is based on the a priori planning and documentation provided by a protocol

• Minimizes arbitrary or "on the fly" decision-making that might introduce bias into study selection or data extraction

• Makes it easier and quicker to draft the final manuscript

• Allows journal reviewers to assess the potential for selective reporting

Prospero is an open access repository for registering an intention to conduct a systematic review with health-related outcomes. When a "protocol" or record is submitted for registration in Prospero, the content is checked to ensure it makes sense, but there is no formal scientific review or critical appraisal conducted. The content in Prospero records falls well short of the information required to meet PRISMA-P reporting standards.

• Booth A, Clarke M, Ghersi D, Moher D, Petticrew M, Stewart L. An international registry of systematic-review protocols. Lancet 2011,377(9760):108–109
• Booth A, Mitchell AS, Mott A, James S, Cockayne S, Gascoyne S, McDaid C. An assessment of the extent to which the contents of PROSPERO records meet the systematic review protocol reporting items in PRISMA-P. F1000Res. 2020 Jul 27;9:773. doi: 10.12688/f1000research.25181.2.