The new NIH Public Access Policy that went into effect on July 1, 2025 requires authors who receive NIH funding to make their Author Accepted Manuscripts freely available in PubMed Central (PMC) immediately at the time of publication. The Author Accepted Manuscript (AAM) is the version that has been peer-reviewed and accepted for publication but is not the final version that has been copyedited and formatted for journal publication.
The policy applies to any manuscript that:
This chart, created by Dana Haugh, Harvey Cushing/John Hay Whitney Medical Library, Yale, can also help explain:

There are a few publishing options that will allow you to comply with the new NIH Public Access Policy.
Some subscription and hybrid journals have policies that allow authors to deposit their AAM immediately to PMC at no cost. The journal's embargo policy for AAMs should be available on their website. You can also use the Open Policy Finder, but it's a good idea to check the journal's website for the most up to date information. If the journal does not have a zero embargo period, ask the journal before submitting if they can make an exception so that you can comply with the NIH public access policy.
When you publish in an open access journal, you retain the copyright of your manuscript which allows you to deposit it into PMC immediately. However, open access journals usually require authors to pay an article processing charge (APC). The library does have some open access publishing agreements that allow eligible authors to publish open access for free with select publishers.
According to NIH notice NOT-OD-25-048, the "NIH recognizes that some peer-reviewed publishing routes may result in publication costs, including, but not limited to, article processing charges (APCs). Publication costs are allowable when they comport with the existing NIH cost principles". To plan for this, come up with a list of potential journals and look up their APC amounts to provide an estimate.
IMPORTANT UPDATE: The NIH announced on July 8 that they would seek to establish new policies for allowable publication costs and later released a Request for Information (NOT-OD-25-138) that outlines five proposed options for limiting, or disallowing, these costs. The proposed effective date is January 1, 2026.
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For further information on issues on journal policies on embargoes, copyright, and publication fees that may affect how authors can comply with the new public access policy, read the Authors Alliance's NIH Public Access Policy: Q&A for Authors.
There are several ways that articles are made available in PMC. The following guidance for determining how your article gets into PMC has been summarized from PMC's For Authors webpage.
Some journals will submit the final, published article directly to PMC. See if your journal is included on the PMC Journal List and lists the following:
Publishers may still deposit articles directly to PMC if an open access arrangement was made AND:
Check the Selective Deposit Collections page to see if your publisher is included. Be sure to confirm with the publisher that they will deposit your article.
If Steps 1 and 2 do not apply, you can deposit your AAM to the NIH Manuscript Submission (NIHMS) system.
IMPORTANT: Publishers should not charge authors to submit to PMC for them. Authors can deposit AAMs into NIHMS for free if they have the copyright permission to do so.
My Bibliography is a tool available in My NCBI that allows you to add citations and link awards to those citations. Once you link your eRA Commons account to My NCBI, you’ll also be able to track the compliance status of your citations in My Bibliography.
With citations and awards added to My Bibliography, you'll be able to create a Research Performance Progress Report (RPPR) that shows compliance with the NIH Public Access Policy.