All states have profiles at this site; the data is typically gathered from state birth defects registries. As of November 15, 2019, the most current report is from 2012. The profiles are an overview rather than an attempt to provide any in-depth local information.
They also have an Annual Reports series that is published in Birth Defects Research.
Use the site search box to look for "birth defects" pennsylvania
It's not perfect but there are some reports that will pop up. A list of some them is found to the left. Unfortunately it doesn't appear to be very easy to retrieve birth defects reports by using the select topic tool at the PeriStats site.